Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP
IntroductionFentanyl and fentanyl analogs (F/FA) have become increasingly common adulterants in copyright prescription pills and illicit street drug mixtures due to their ease of synthesis and exceedingly high potency.The ongoing epidemic of fatal overdoses fueled by F/FA continues to highlight the need for longer-acting therapies than naloxone (NL